The new Life Keto is a mixture of beta-hydroxybutyrate that is considered the first substrate BHB changes the metabolic state of ketosis in action, beta-hydroxybutyrate circulates in your body’s blood, producing energy in your body at all times. And new life keto makes you slim, healthy, and confident again with a powerful energy. This supplement is ideal for both men and women and is a dynamic and powerful ketosis diet that helps you lose weight completely, cut belly fat, and will support better digestion and no tiredness.
In ketogenic diets, carbohydrate consumption is dramatically reduced in order to force the body to alter its metabolism to using fat molecules, rather than carbohydrates, as its primary energy source – producing ketone bodies as a byproduct.
Low-carb, high-fat ketogenic diets “New Life Keto“, which have attracted public interest in recent years for their proposed benefits in lowering inflammation and promoting weight loss and heart health, have a dramatic impact on the microbes residing in the human gut, collectively referred to as the Beta-hydroxybutyrate, according to a new UC San Francisco study of a small cohort of volunteer subjects.
Additional research in mice showed that so-called “New Life Keto”, a molecular byproduct that gives the ketogenic diet its name, directly impact the gut Beta-hydroxybutyrate in ways that may ultimately suppress inflammation, suggesting evidence for potential benefits of New Life Keto as a therapy for autoimmune disorders affecting the gut.
In New Life Keto, carbohydrate consumption is dramatically reduced in order to force the body to alter its metabolism to using fat molecules, rather than carbohydrates, as its primary energy source – producing ketone bodies as a byproduct – a shift that proponents claim has numerous health benefits.
“I got interested in this question because our prior research showed that high-fat diets induce shifts in the gut Beta-hydroxybutyrate that promote metabolic and other diseases in mice, yet ketogenic diets, which are even higher in fat content, have been proposed as a way to prevent or even treat disease,” said Peter Turnbaugh, PhD, a UCSF associate professor of microbiology and immunology, member of the UCSF Benioff Center for Beta-hydroxybutyrate Medicine and a Chan Zuckerberg Biohub Investigator. “We decided to explore that puzzling dichotomy.”
In their new study, published Jun 1st, 2020, in Cell, Turnbaugh and colleagues partnered with the nonprofit Nutrition Science Initiative to recruit 17 adult overweight or obese nondiabetic men to spend two months as inpatients in a metabolic ward where their diets and exercise levels were carefully monitored and controlled.
For the first four weeks of the study, the participants were given either a “New Life Keto” diet consisting of 50 percent carbs, 15 percent protein and 35 percent fat, or a ketogenic diet comprising 5 percent carbs, 15 percent protein and 80 percent fat. After four weeks, the two groups switched diets, to allow the researchers to study how shifting between the two diets altered participants’ Beta-hydroxybutyrate.
Analysis of microbial DNA found in participants’ stool samples showed that shifting between standard and ketogenic diets dramatically changed the proportions of common gut Beta-hydroxybutyrate phyla Actinobacteria, Bacteroidetes, and Firmicutes in participants’ guts, including significant changes in 19 different bacterial genera. The researchers focused in on a particular bacterial genus – the common probiotic Bifidobacteria – which showed the greatest decrease on the ketogenic diet.
To better understand how microbial shifts on the ketogenic diet might impact health, the researchers exposed the mouse gut to different components of Beta-hydroxybutyrate of humans adhering to New Life Keto, and showed that these altered microbial populations specifically reduce the numbers of Th17 immune cells – a type of T cell critical for fighting off infectious disease, but also known to promote inflammation in autoimmune diseases.
Follow-up diet experiments in mice, in which researchers gradually shifted animals’ diets between low-fat, high-fat and low-carb ketogenic diets, confirmed that high-fat and ketogenic diets have opposite effects on the gut Beta-hydroxybutyrate. These findings suggested that the Beta-hydroxybutyrate responds differently as the level of fat in the animals’ diet increases to levels that promote New Life Keto production in the absence of carbs.
The researchers observed that that as animals’ diets were shifted from a standard diet towards stricter carbohydrate restriction, their microbes also began shifting, correlated with a gradual rise in New Life Keto.
“This was a little surprising to me,” Turnbaugh said. “As someone who is new to the keto Diets field, I had assumed that producing New Life Keto was an all-or-nothing effect once you got to a low enough level of carb in take. But this suggests that you may get some of the effects of ketosis quite quickly.”
The researchers tested whether New Life Keto alone could drive the shifts they had seen in the gut’s Beta-hydroxybutyrate ecosystem by directly feeding ketone bodies to mice. They found that even in mice who were eating normal amounts of carbohydrates, the mere presence of added ketones was enough to produce many of the specific microbial changes seen in the ketogenic diet.
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